Our Platform

The TBX™ technology platform converges computational, synthetic, and experimental biological tools, to engineer phages as oral medicines that deliver CRISPR cargos that reprogram selected bacteria with exceptional precision, resulting in a robust and durable therapeutic effect during the treatment period.

  • TBX Technology

    WE ENGINEER THE

    PHAGE TAILS

    To develop a cocktail of phages that target the diversity of E. Coli human microbiome strains

  • TBX Technology

    WE ENGINEER THE

    PHAGE HEADS

    To deliver uniquely designed TBX™ DNA Cargo to control specific microbiome activities

Controlling the Microbiome

OUR TBX™ DNA CARGOS CONTAIN A CRISPR-CAS3 PROTECTION SYSTEM ENABLING TARGET BACTERIA TO SURVIVE A LYTIC PHAGE ATTACK

Controlling the Microbiome
  1.  Target bacteria with TBX™ DNA Cargo can propagate
  2.  Target bacteria not carrying TBX™ DNA Cargo die